Papers

TINS_image.jpg
Frontiers_generalization_review_2019.jpg
Nature_CA2_2018_snip.jpg

“A subtle thought in error may yet give rise to fruitful inquiry that can establish truths of great value”
- Issac Asimov -

 

Manuscripts / Preprints / Submitted / In Prep

(2/4) Asok A. (In Preparation) Circular RNAs embed pieces of real-world sensory information into an episodic memory. Incomplete Draft Link. (need help to finish).

Reyes, N.S., Diaz, P.A.S., Manas, R.N., Ruiz-Pino, A., Nomura, Y., de Solis, C.A., Schulkin, J., Asok A. & Leroy, F. (Submitted) Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum supports social novelty preference. BioRxiv Preprint. (2022)

(1/4) Asok A., Leroy, F., Parro, C., de Solis, C.A., Ford, L. Fitzpatrick, M.N., Kalmbach, A. Neve, R., Rayman, J.B. & Kandel, E.R. (In Revision - Nature Communications - 2022). A multisensory circuit for gating intense aversive experiences. Preprint.

 

Ford, L., Asok A., Tripp, A.D., Parro, C., Fitzpatrick, M., de Solis, C.A., Shafiian, N., Fioriti, L., Soni, R.J. & Kandel, E.R. (In Revision - PNAS - 2022). The low complexity motif of cytoplasmic polyadenylation element binding protein 3 (CPEB3) is critical for the trafficking of its targets in neurons. Preprint

Asok A. (In Preparation) MADe in America (Book).

2022

Asok A. (2022). Editorial: Brain Modifications in Response to Stress: From Cellular to Circuit Reorganization. Frontiers in Systems Neuroscience. LINK 

Kalmbach, A., Winiger, V., Jeong, N., Asok A., Gallistel, C.R., Balsam, P.D. & Simpson, E.H. (Nature Communications) Mesolimbic dopamine can encode reward availability on multiple time scales. PMID: 35778414

2021

Leroy, F., De Solis, C., Boyle, L., Bock, T., Olfaro, O., Oliva, A., Buss, E., Morton, S., Asok A., Kandel, E.R., Siegelbaum, S.A. (2021). Enkephalin release by VIP neurons mediates hippocampal CA2 inhibitory plasticity and the formation of CA2-dependent social memory. Molecular Psychiatry. PMID: 33990774.

2020

Scherma M., Qvist, J.S., Asok A., Huang, S.S.C., Deidda, M., Wei, Y.B., Soni, R.K., Fratta, W., Fadda, P., Kandel, E.R., Kandel, D.B. & Melas, P.A. (2020). Cannabinoid exposure in adolescence modifies the molecular response to cocaine. Proceedings of the national academy of sciences. PMID: 32312805.

2019

Asok, A., Leroy, F., Rayman, J. B., & Kandel, E. R. (2019). Molecular mechanisms of the memory trace. Trends in neurosciences. PMID: 30391015.

Asok, A., Hijazi, J., Harvey, L. R., Kosmidis, S., Kandel, E. R., & Rayman, J. B. (2019). Sex differences in remote contextual fear generalization in mice. Frontiers in behavioral neuroscience, 13. PMID: 30967765.

Asok, A., Kandel, E. R., & Rayman, J. B. (2019). The neurobiology of fear generalization. Frontiers in behavioral neuroscience, 12. PMID: 30697153.

2018

Leroy, F., Park, J., Asok, A., Brann, D. H., Meira, T., Boyle, L. M., ... & Siegelbaum, S. A. (2018). A circuit from hippocampal CA2 to lateral septum disinhibits social aggression. Nature, 564(7735), 213. PMID: 30518859.

Asok, A., Draper, A., Hoffman, A. F., Schulkin, J., Lupica, C. R., & Rosen, J. B. (2018). Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear. Molecular psychiatry, 23(4), 914. PMID: 28439099.

Jablonski, S. A., Robinson-Drummer, P. A., Schreiber, W. B., Asok, A., Rosen, J. B., & Stanton, M. E. (2018). Impairment of the context preexposure facilitation effect in juvenile rats by neonatal alcohol exposure is associated with decreased Egr-1 mRNA expression in the prefrontal cortex. Behavioral neuroscience, 132(6), 497. PMID: 30346189.

 

Dagan, O., Asok, A., Steele, H., Steele, M., & Bernard, K. (2018). Attachment security moderates the link between adverse childhood experiences and cellular aging. Development and psychopathology, 30(4), 1211-1223. PMID: 29229013.

2017

Blaze, J., Asok, A., Borrelli, K., Tulbert, C., Bollinger, J., Ronca, A. E., & Roth, T. L. (2017). Intrauterine exposure to maternal stress alters Bdnf IV DNA methylation and telomere length in the brain of adult rat offspring. International journal of developmental neuroscience, 62, 56-62. PMID: 28330827.

Murawski, N. J. & Asok, A. (2017). Understanding the contributions of visual stimuli to contextual fear conditioning: a proof-of-concept study using LCD screens. Neuroscience letters, 637, 80-84. PMID: 27888041 / BioRꭓiv Preprint.

2016

Asok, A., Schulkin, J., & Rosen, J. B. (2016). Corticotropin releasing factor type-1 receptor antagonism in the dorsolateral bed nucleus of the stria terminalis disrupts contextually conditioned fear, but not unconditioned fear to a predator odor. Psychoneuroendocrinology, 70, 17-24. PMID: 27153520.

 

Chakraborty, T., Asok, A., Stanton, M. E., & Rosen, J. B. (2016). Variants of contextual fear conditioning induce differential patterns of Egr-1 activity within the young adult prefrontal cortex. Behavioural brain research, 302, 122-130. PMID: 26778782.

2015

 

Blaze, J., Asok, A., & Roth, T. L. (2015). Long-term effects of early-life caregiving experiences on brain-derived neurotrophic factor histone acetylation in the adult rat mPFC. Stress, 18(6), 607-615. PMID: 26305287.

 

Ayers, L. W., Asok, A., Blaze, J., Roth, T. L., & Rosen, J. B. (2016). Changes in dam and pup behavior following repeated postnatal exposure to a predator odor (TMT): A preliminary investigation in long‐evans rats. Developmental psychobiology, 58(2), 176-184. PMID: 26394891.

 

Rosen, J. B., Asok, A., & Chakraborty, T. (2015). The smell of fear: innate threat of 2, 5-dihydro-2, 4, 5-trimethylthiazoline, a single molecule component of a predator odor. Frontiers in neuroscience, 9, 292. PMID: 26379483.

 

Blaze, J., Asok, A., & Roth, T. L. (2015). The long-term impact of adverse caregiving environments on epigenetic modifications and telomeres. Frontiers in behavioral neuroscience, 9, 79. PMID: 25904853.

2014

 

Asok, A., Bernard, K., Rosen, J. B., Dozier, M. & Roth, T. L. (2014). Infant-caregiver experiences alter telomere length in the brain. PLoS one, 9(7), e101437. PMID: 24983884.

 

Schreiber W. B., Asok, A., Jablonski, S. A., Rosen, J. B. & Stanton, M. E. (2014). Egr-1 mRNA expression patterns in the prefrontal cortex, hippocampus, and amygdala during variants of contextual fear conditioning in adolescent rats. Brain Research, 1576, 63-72. PMID: 24976583.

2013

 

Asok, A., Ayers, L. W., Awoyemi, B., Schulkin, J. & Rosen, J. B. (2013). Immediate early gene and neuropeptide expression following exposure to the predator odor 2,5-dihydro-2,4,5-trimethylthiazoline (TMT). Behavioural Brain Research, 248, 85-93. PMID: 23583519.

 

Asok, A., Schreiber W. B., Jablonski, S. A., Rosen, J. B. & Stanton, M. E. (2013). Egr-1 increases in the prefrontal cortex following training in the context preexposure facilitation effect (CPFE) paradigm. Neurobiology of Learning and Memory, 106, 145-153. PMID: 23973447.

 

Ayers, L.W., Asok, A., Heyward, F. D. & Rosen, J. B. (2013). Freezing to the predator odor 2,4,5 dihydro 2,5 trimethylthiazoline (TMT) is disrupted by olfactory bulb removal but not trigeminal deafferentation. Behavioural Brain Research, 253, 54-59. PMID: 23831303.

 

Asok, A., Bernard, K., Roth, T. L., Rosen, J. B. & Dozier, M. (2013). Parental responsiveness moderates the association between early-life stress and reduced telomere length. Development and Psychopathology, 25(3), 577-585. PMID: 23527512.

google-scholar-2-512.png

Google Scholar

researchgate.png

Researchgate

hiclipart_edited.png

Twitter

Screenshot 2022-05-10 002114_edited_edited_edited.jpg

Loop

ELUCIDATING THE NEUROBIOLOGAL SUBSTRATES OF MEMORY & EMOTION

LabLogo_cropped_Lab Removed_edited.png
LabLogo_cropped_Lab Removed_edited.png